In 1951, cancerous cells from Henrietta Lacks lead to breakthroughs that change the face of medicine forever. Aided by writer Rebecca Skloot, Deborah Lacks embarks on a quest to learn about the mother she never knew. Director: George C. Wolfe Cast: Oprah Winfrey, Rose Byrne, Renée Elise Goldsberry, Courtney B. Vance, Reg E. Cathey, Ruben Santiago-Hudson Oprah Winfrey, also known mononymously as Oprah, is an American talk show host, television producer, actress, author, and media proprietor. She is best known for her talk show, The Oprah Winfrey Show, broadcast from Chicago, which ran in national syndication for 25 years, from 1986 to 2011. Dubbed the "Queen of All Media," she was the richest African-American of the 20th century and was once the world's only Black billionaire. By 2007, she was often ranked as the most influential woman in the world.
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